PulmoJet® Dry Powder Inhaler (DPI) by Sanofi Generics

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DESIGN DETAILS
DESIGN NAME:
PulmoJet®

PRIMARY FUNCTION:
Dry Powder Inhaler (DPI)

INSPIRATION:
Correct inhaler use is essential for effective drug delivery but serious errors are common with current inhaler products, which may lead to poor disease control (Lavorini & Corbetta, 2008; Molimard, et al., 2003; Melani AS, et al., 2011). The respiratory market has increased opportunities for new and innovative products to provide better patient benefits and value (Lavorini & Corbetta, 2008; Thomas, et al, 2009; Lavorini, et al., 2008; Lavorini, 2013; Virchow, et al., 2008).

UNIQUE PROPERTIES / PROJECT DESCRIPTION:
PulmoJet® is an innovative, simple-to-use dry-powder inhaler with dose feedback mechanisms, giving physicians and patients confidence that the correct dose is delivered. It has a simple design for reliable and effective drug delivery. PulmoJet® is used by following 3 simple steps: open, inhale and close. The device includes audio and visual confirmation on correct dosing.

OPERATION / FLOW / INTERACTION:
PulmoJet® is an innovative, simple-to-use and easy-to-teach inhaler with multiple mechanisms, which is less prone to serious handling errors (Chrystyn et al., 2016). The device has three simple steps for effective use: open, inhale, close. The dose indicator shows you how many doses you have remaining. The green dose ready window will disappear after taking a dose. To load the next dose of medicine, the white cover is twisted back on to the inhaler until it clicks.

PROJECT DURATION AND LOCATION:
-

FITS BEST INTO CATEGORY:
Scientific Instruments, Medical Devices and Research Equipment Design

PRODUCTION / REALIZATION TECHNOLOGY:
Stainless steel, silicon, polypropylene, thermoplastic elastomer and other materials have been used in the construction of the PulmoJet® design. The breathe actuator is responsible for the protection and release of the loaded dose. The de-aggregator ensures the medication particles are the ideal size for inhalation. Medication is stored in the protected powder reservoir and the formulation is kept under pressure by a spring which fixes the position of the powder.

SPECIFICATIONS / TECHNICAL PROPERTIES:
29.5 mm x 29.5 mm x 99 mm

TAGS:
DPI, simple-to-use, easy-to-teach, inhaler, open inhale close

RESEARCH ABSTRACT:
A Sanofi-led HI-TEC (Handling Inhalers – Technique Error Comparison) study assessed use and serious handling errors with PulmoJet® versus commonly used DPIs in asthma and COPD patients in a real-life setting. There was a significant risk reduction in serious handling errors reported from the randomized, crossover study. Patients using PulmoJet® made significantly fewer serious handling errors versus commonly used DPIs when trained using an instructional leaflet, and this benefit increases after additional video training (Chrystyn et al., 2016).

CHALLENGE:
The latest GINA and GOLD guidelines highlight the importance of inhaler technique in good disease control. Up to 54% of asthma and COPD patients using their DPI (dry powder inhaler) make serious handling errors (Al-Jahdali, et al., 2013). Failure to use inhalers correctly may potentially result in poor asthma and COPD control, increased costs and greater risk to the patient. Evidence has shown that reducing handling errors may lead to improved treatment adherence, and better disease and symptom control (Al-Jahdali, et al., 2013; Yildiz, et al., 2014; Small, et al., 2011; Voshaar, et al., 2014). PulmoJet® is an innovative DPI designed to reduce the serious handling errors frequently reported with the common devices used by asthma and COPD patients.

ADDED DATE:
2016-02-26 11:46:28

TEAM MEMBERS (1) :


IMAGE CREDITS:
Sanofi Generics

Visit the following page to learn more: http://www.sanofigenerics.com/
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CLIENT/STUDIO/BRAND DETAILS
NAME:
Sanofi Generics

PROFILE:
With the creation of Sanofi Generics, Sanofi strengthens its commitment to provide patients around the world, reliable access to valuable and affordable high-quality, safe and effective medicines. In addition to being effective therapies, generic medicines also play an important role by enabling health care systems to invest savings in the development of future, innovative treatments. Sanofi Generics operates worldwide using already strong generics brands like Zentiva, Medley, Genfar, Winthrop and Globalpharma with about 700 INN and selling 900 M boxes per year that represents more than 20 billion standard units. Because patients are at the heart of our approach, every day, women and men who are working for Sanofi Generics strive to identify and fulfill patients‘ needs. Sanofi Generics is using innovation and adapted business models all over the world to make affordable, high quality generic medicines available to patients and to develop strategic partnership with healthcare management stakeholders. The mission of the global Generics Franchise is to complement Sanofi’s offering to patients by selecting, developing and manufacturing a portfolio of competitive generic products to maximize growth opportunities, synergistic with the overall footprint of Sanofi within key geographies. With its generics products, Sanofi strengthens its commitment to provide reliable access to valuable and affordable high-quality, safe and effective medicines. In addition to being effective therapies, generic medicines also play an important role by enabling health care systems to invest savings in the development of future, innovative treatments. Sanofi Generics operates worldwide using already strong generic brands like Zentiva, Medley, Genfar, Winthrop and Globalpharma.

NOMINATION DETAILS

Pulmojet® Dry Powder Inhaler (dpi) by Sanofi Generics is a Nominee in Scientific Instruments, Medical Devices and Research Equipment Design Category.

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AWARD DETAILS

Pulmojet® Dry Powder Inhaler (dpi) by Sanofi Generics is Winner in Scientific Instruments, Medical Devices and Research Equipment Design Category, 2015 - 2016.



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